Home button wont work even after replacement

So I recently installed a new screen on a 5S, and about a week later the home button stopped working. I opened up to check the flex cable, and it was intact. I tried switching the button, but no luck. Then tried to switch the charge-flex but same story. What to do?

I have seen this on another 5S before, where no screen replacement was performed. Everything is as it should be, but the button wont react.